CD82 antibody (C-Term)
Quick Overview for CD82 antibody (C-Term) (ABIN2789464)
Target
See all CD82 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- DYVQAQVKCC GWVSFYNWTD NAELMNRPEV TYPCSCEVKG EEDNSLSVRK
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Predicted Reactivity
- Human: 100%, Yeast: 100%
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Characteristics
- This is a rabbit polyclonal antibody against CD82. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 267 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD82
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Alternative Name
- CD82
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Background
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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
Protein Interaction Partner: GGT1, CD81, CD53, UBC, LGALS3BP, AMFR, VANGL1, IGSF8, ITGA3, NUP88, PTGFRN, ITGB2, ITGA4, ERBB3, CD4, ERBB2, CD63, ITGA6, HLA-DRA, HLA-DMB, HLA-DMA, ITGB1, EGFR, HBEGF, CANX, LRP1, CD19, ITGAL, HLA-DOB, CD46, CD151, CD9, RUVBL1, POLR2A, KAT5, CTNNB1, RUVB
Protein Size: 267 -
Molecular Weight
- 29 kDa
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Gene ID
- 3732
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NCBI Accession
- NM_002231, NP_002222
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UniProt
- P27701
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Pathways
- p53 Signaling
Target
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