Cathepsin H antibody (C-Term)

Catalog No. ABIN2789470

This Rabbit Polyclonal antibody specifically detects Cathepsin H in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for Cathepsin H antibody (C-Term) (ABIN2789470)

Target: Cathepsin H (CTSH)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin H antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin H Antibody

Binding Specificity: C-Term

Sequence: DFMMYRTGIY SSTSCHKTPD KVNHAVLAVG YGEKNGIPYW IVKNSWGPQW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CTSH. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 335 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cathepsin H

Target: Cathepsin H (CTSH)

Alternative Name: CTSH

Background: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.
Alias Symbols: ACC-4, ACC-5, CPSB, DKFZp686B24257, MGC1519, minichain
Protein Interaction Partner: XRN1, UBC, CSTB, CSTA, SFTPB, BGLAP,
Protein Size: 335

Molecular Weight: 24 kDa

Gene ID: 1512

NCBI Accession: NM_004390, NP_004381

UniProt: P09668

Pathways: Positive Regulation of Endopeptidase Activity