RGR antibody (C-Term)

Catalog No. ABIN2789477

This Rabbit Polyclonal antibody specifically detects RGR in WB. It exhibits reactivity toward Human, Mouse, Horse and Pig.

Quick Overview for RGR antibody (C-Term) (ABIN2789477)

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Reactivity: Human, Mouse, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGR Antibody

Binding Specificity: C-Term

Sequence: GKSGHLQVPA LIAKMVPTIN AINYALGNEM VCRGIWQCLS PQKREKDRTK

Predicted Reactivity: Horse: 83%, Human: 100%, Mouse: 85%, Pig: 83%

Characteristics: This is a rabbit polyclonal antibody against RGR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 253 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Alternative Name: RGR

Background: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).
Alias Symbols: RP44
Protein Interaction Partner: KIAA1279, RDH5,
Protein Size: 253

Molecular Weight: 28 kDa

Gene ID: 5995

NCBI Accession: NM_001012722, NP_001012740