MADCAM1 antibody (C-Term)

Catalog No. ABIN2789480

This Rabbit Polyclonal antibody specifically detects MADCAM1 in WB. It exhibits reactivity toward Human.

Quick Overview for MADCAM1 antibody (C-Term) (ABIN2789480)

Target: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MADCAM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MADCAM1 Antibody

Binding Specificity: C-Term

Purpose: MADCAM1 Antibody - C-terminal region

Sequence: TTSPESPDTT SPESPDTTSQ EPPDTTSPEP PDKTSPEPAP QQGSTHTPRS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MADCAM1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63390-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MADCAM1

Target: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Alternative Name: MADCAM1

Background:

Background Information: The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.

Gene Name: Mucosal vascular addressin cell adhesion molecule 1

Alternative Symbols: MACAM1

Protein Name: Mucosal addressin cell adhesion molecule 1

Molecular Weight: 42kDa

Gene ID: 8174

NCBI Accession: NP_570116

UniProt: Q13477