MADCAM1 antibody (C-Term)
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- Target See all MADCAM1 Antibodies
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MADCAM1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TTSPESPDTT SPESPDTTSQ EPPDTTSPEP PDKTSPEPAP QQGSTHTPRS
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MADCAM1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MADCAM1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 382 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Alternative Name
- MADCAM1 (MADCAM1 Products)
- Synonyms
- MACAM1 antibody, AV211525 antibody, mucosal vascular addressin cell adhesion molecule 1 antibody, MADCAM1 antibody, Madcam1 antibody
- Background
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The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: MACAM1
Protein Interaction Partner: ITGB7, ITGA4, CD44, MADCAM1,
Protein Size: 382 - Molecular Weight
- 42 kDa
- Gene ID
- 8174
- NCBI Accession
- NM_130760, NP_570116
- UniProt
- Q13477
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