SLC22A5 antibody (C-Term)

Catalog No. ABIN2789486

This Rabbit Polyclonal antibody specifically detects SLC22A5 in WB. It exhibits reactivity toward Human, Rat, Cow, Horse, Guinea Pig, Dog, Pig and Rabbit.

Quick Overview for SLC22A5 antibody (C-Term) (ABIN2789486)

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Reactivity: Human, Rat, Cow, Horse, Guinea Pig, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC22A5 Antibody

Binding Specificity: C-Term

Purpose: SLC22A5 Antibody - C-terminal region

Sequence: GIVVPSTIFD PSELQDLSSK KQQSHNILDL LRTWNIRMVT IMSIMLWMTI

Predicted Reactivity: Cow: 100%, Dog: 85%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against SLC22A5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63404-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC22A5

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Alternative Name: SLC22A5

Background:

Background Information: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Gene Name: Solute carrier family 22 (organic cation/carnitine transporter), member 5

Alternative Symbols: CDSP, OCTN2

Protein Name: Solute carrier family 22 member 5

Molecular Weight: 61kDa

Gene ID: 6584

NCBI Accession: NP_003051

UniProt: O76082