Translin antibody (Middle Region)

Catalog No. ABIN2789513

The Rabbit Polyclonal anti-Translin antibody has been validated for WB. It is suitable to detect Translin in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Translin antibody (Middle Region) (ABIN2789513)

Target: Translin (TSN)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Translin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Translin Antibody

Binding Specificity: Middle Region

Sequence: LVTREAVTEI LGIEPDREKG FHLDVEDYLS GVLILASELS RLSVNSVTAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against TSN. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 228 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Translin

Target: Translin (TSN)

Alternative Name: TSN

Background: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms.
Alias Symbols: BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN
Protein Interaction Partner: UBC, WDR12, NSUN2, TSNAX, TBCD, SHMT1, PPP3CA, PFDN1, NRD1, ETF1, ATP6V1C1, SETSIP, FAM129B, P3H1, ELAC2, SNX6, MYC, GIT2, TSN, EIF4A3, MAGOH, UBA6, VPS29, UCHL3, TTC4, ZBTB18, PPP1R15A, HCVgp1,
Protein Size: 228

Molecular Weight: 25 kDa

Gene ID: 7247

NCBI Accession: NM_004622, NP_004613

UniProt: Q15631