Translin antibody (Middle Region)

Catalog No. ABIN2789513

Product Details anti-Translin Antibody

Target: Translin (TSN)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Translin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVTREAVTEI LGIEPDREKG FHLDVEDYLS GVLILASELS RLSVNSVTAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against TSN. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 228 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Translin

Target: Translin (TSN)

Alternative Name: TSN (TSN Products)

Synonyms: tsn antibody, MGC52533 antibody, TSN antibody, CG11761 antibody, Dmel\\CG11761 antibody, TB-RBP antibody, BCLF-1 antibody, C3PO antibody, RCHF1 antibody, REHF-1 antibody, TBRBP antibody, TRSLN antibody, 2610034C24Rik antibody, AU040286 antibody, translin L homeolog antibody, translin antibody, haloacid dehalogenase antibody, Translin antibody, tsn.L antibody, TSN antibody, trsn antibody, MMAH_RS03470 antibody, TAGG_RS05275 antibody, Igag_0962 antibody, MFER_RS03645 antibody, DESMU_RS01315 antibody, ARCVE_RS05265 antibody, MZHIL_RS01310 antibody, Tsn antibody

Background: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms.
Alias Symbols: BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN
Protein Interaction Partner: UBC, WDR12, NSUN2, TSNAX, TBCD, SHMT1, PPP3CA, PFDN1, NRD1, ETF1, ATP6V1C1, SETSIP, FAM129B, P3H1, ELAC2, SNX6, MYC, GIT2, TSN, EIF4A3, MAGOH, UBA6, VPS29, UCHL3, TTC4, ZBTB18, PPP1R15A, HCVgp1,
Protein Size: 228

Molecular Weight: 25 kDa

Gene ID: 7247

NCBI Accession: NM_004622, NP_004613

UniProt: Q15631