BAG1 antibody (N-Term)

Catalog No. ABIN2789515

The Rabbit Polyclonal anti-BAG1 antibody (ABIN2789515) specifically detects BAG1 in WB. The antibody is reactive with Human, Dog, Horse, Cow, Pig, Zebrafish (Danio rerio) and Rabbit samples.

Quick Overview for BAG1 antibody (N-Term) (ABIN2789515)

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Reactivity: Human, Dog, Horse, Cow, Pig, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BAG1 Antibody

Binding Specificity: N-Term

Purpose: BAG1 Antibody - N-terminal region

Sequence: LIFKGKSLKE METPLSALGI QDGCRVMLIG KKNSPQEEVE LKKLKHLEKS

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 91%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against BAG1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63477-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BAG1

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Alternative Name: BAG1

Background:

Background Information: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Gene Name: BCL2-associated athanogene

Alternative Symbols: HAP, BAG-1, RAP46

Protein Name: BAG family molecular chaperone regulator 1

Molecular Weight: 25kDa

Gene ID: 573

NCBI Accession: NP_001165886

UniProt: Q99933