Exonuclease 1 antibody (N-Term)

Catalog No. ABIN2789520

This Rabbit Polyclonal antibody specifically detects Exonuclease 1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Zebrafish (Danio rerio), Horse and Saccharomyces cerevisiae.

Quick Overview for Exonuclease 1 antibody (N-Term) (ABIN2789520)

Target: Exonuclease 1 (EXO1)

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Zebrafish (Danio rerio), Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Exonuclease 1 Antibody

Binding Specificity: N-Term

Sequence: ILVFDGCTLP SKKEVERSRR ERRQANLLKG KQLLREGKVS EARECFTRSI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against EXO1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 803 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: EXO1

Background: This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Alias Symbols: HEX1, hExoI
Protein Interaction Partner: YWHAB, MLH1, PCNA, UBC, SUMO2, YWHAQ, YWHAZ, YWHAH, YWHAG, YWHAE, MSH2, KPNA4, KPNB1, SFN, ATM, PMS2, PMS1, BLM, MSH3,
Protein Size: 803

Molecular Weight: 89 kDa

Gene ID: 9156

NCBI Accession: NM_003686, NP_003677

UniProt: Q9UQ84

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response