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Neural Wiskott-Aldrich syndrome protein (WASL) (Middle Region) antibody

WASL Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789523
  • Target See all Neural Wiskott-Aldrich syndrome protein (WASL) Antibodies
    Neural Wiskott-Aldrich syndrome protein (WASL)
    Binding Specificity
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 38
    • 22
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
    Host
    • 35
    • 3
    • 2
    Rabbit
    Clonality
    • 29
    • 11
    Polyclonal
    Conjugate
    • 19
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Un-conjugated
    Application
    • 19
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ISHTKEKKKG KAKKKRLTKA DIGTPSNFQH IGHVGWDPNT GFDLNNLDPE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against WASL. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product WASL Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 505 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Neural Wiskott-Aldrich syndrome protein (WASL)
    Alternative Name
    WASL (WASL Products)
    Synonyms
    N-WASP antibody, TRS4 antibody, NWASP antibody, WASPB antibody, 2900021I12Rik antibody, 3110031I02Rik antibody, zgc:158395 antibody, n-wasp antibody, nwasp antibody, wasl antibody, zgc:55478 antibody, zgc:77237 antibody, Wiskott-Aldrich syndrome-like antibody, Wiskott-Aldrich syndrome like antibody, Wiskott-Aldrich syndrome-like (human) antibody, Wiskott-Aldrich syndrome-like a antibody, Wiskott-Aldrich syndrome like L homeolog antibody, Wiskott-Aldrich syndrome-like b antibody, Wasl antibody, WASL antibody, wasla antibody, wasl.L antibody, waslb antibody
    Background
    The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.
    Alias Symbols: DKFZp779G0847, MGC48327, N-WASP, NWASP
    Protein Interaction Partner: RHOJ, ARPC3, RNF8, NCK2, WIPF1, SDCBP, PTK6, GRB2, IQGAP1, WWOX, SNX9, APBB1, PRPF40A, FNBP1L, FNBP1, TRIP10, PSTPIP1, ACTG1, SORBS3, ACTR2, ACTR3, LCK, CDC42, RPL7AP66, ZNF395, BAIAP2, ARPC1B, FCHSD2, IPO5, HP, HSP90AB1, HSP90AA1, SRC, WASF2, APP, WIPF2,
    Protein Size: 505
    Molecular Weight
    56 kDa
    Gene ID
    8976
    NCBI Accession
    NM_003941, NP_003932
    UniProt
    O00401
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