SPRR1B antibody (Middle Region)

Catalog No. ABIN2789544

Product Details anti-SPRR1B Antibody

Target: SPRR1B (Small Proline Rich Protein 1B (SPRR1B))

Binding Specificity: Middle Region

Reactivity: Human, Pig, Rabbit, Rat, Cow, Horse, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRR1B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Sequence: PCHPKVPEPC HPKVPEPCQP KVPEPCHPKV PEPCPSIVTP APAQQKTKQK

Predicted Reactivity: Cow: 85%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 92%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against SPRR1B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 89 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPRR1B

Target: SPRR1B (Small Proline Rich Protein 1B (SPRR1B))

Alternative Name: SPRR1B (SPRR1B Products)

Synonyms: CORNIFIN antibody, GADD33 antibody, SPRR1 antibody, SPRR1B antibody, small proline rich protein 1B antibody, small proline-rich protein antibody, small proline-rich protein 1B antibody, SPRR1B antibody, SPRP antibody, Sprr1b antibody

Background: SPRR1B is a cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. SPRR1B can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Alias Symbols: CORNIFIN, GADD33, MGC61901, SPRR1
Protein Interaction Partner: Rab5c,
Protein Size: 89

Molecular Weight: 10 kDa

Gene ID: 6699

NCBI Accession: NM_003125, NP_003116

UniProt: P22528