Galanin Receptor 1 antibody (C-Term)

Catalog No. ABIN2789546

This Rabbit Polyclonal antibody specifically detects Galanin Receptor 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Galanin Receptor 1 antibody (C-Term) (ABIN2789546)

Target: Galanin Receptor 1 (GALR1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galanin Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Galanin Receptor 1 Antibody

Binding Specificity: C-Term

Purpose: GALR1 Antibody - C-terminal region

Sequence: CLAYSNSSVN PIIYAFLSEN FRKAYKQVFK CHIRKDSHLS DTKESKSRID

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GALR1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63562-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Galanin Receptor 1

Target: Galanin Receptor 1 (GALR1)

Alternative Name: GALR1

Background:

Background Information: The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.

Gene Name: Galanin receptor 1

Alternative Symbols: GALNR, GALNR1

Protein Name: Galanin receptor type 1

Molecular Weight: 38kDa

Gene ID: 2587

NCBI Accession: NP_001471

UniProt: P47211

Pathways: cAMP Metabolic Process