HRH4 antibody (Middle Region)

Catalog No. ABIN2789548

This Rabbit Polyclonal antibody specifically detects HRH4 in WB. It exhibits reactivity toward Human and Pig.

Quick Overview for HRH4 antibody (Middle Region) (ABIN2789548)

Target: HRH4 (Histamine Receptor H4 (HRH4))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HRH4 Antibody

Binding Specificity: Middle Region

Purpose: HRH4 Antibody - middle region

Sequence: GRLSSRRSLS ASTEVPASFH SERQRRKSSL MFSSRTKMNS NTIASKMGSF

Predicted Reactivity: Human: 100%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against HRH4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63567-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HRH4

Target: HRH4 (Histamine Receptor H4 (HRH4))

Alternative Name: HRH4

Background:

Background Information: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Histamine receptor H4

Alternative Symbols: H4, H4R, BG26, HH4R, AXOR35, GPRv53, GPCR105

Protein Name: Histamine H4 receptor

Molecular Weight: 33kDa

Gene ID: 59340

NCBI Accession: NP_001137300

UniProt: B2KJ48