Integrin beta 3 antibody (N-Term)

Catalog No. ABIN2789560

The Rabbit Polyclonal anti-Integrin beta 3 antibody has been validated for WB. It is suitable to detect Integrin beta 3 in samples from Human, Rat, Cow, Dog, Rabbit, Sheep, Horse and Guinea Pig.

Quick Overview for Integrin beta 3 antibody (N-Term) (ABIN2789560)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human, Rat, Cow, Dog, Rabbit, Sheep, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin beta 3 Antibody

Binding Specificity: N-Term

Sequence: PLGSPRCDLK ENLLKDNCAP ESIEFPVSEA RVLEDRPLSD KGSGDSSQVT

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 92%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against ITGB3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 788 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: ITGB3

Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Alias Symbols: CD61, GP3A, GPIIIa, GT, BDPLT2
Protein Interaction Partner: EPHA2, THBS1, SYK, TENC1, ANGPTL3, ITGB3BP, ITGA2B, PDPK1, NUMB, DAB1, DOK1, ILK, DAB2, PTK2B, PTK2, SHC1, EPS8, P2RY2, ITGAV, VTN, KDR, TGM2, SRC, THY1, TLN1, CD36, PDGFRA, ITGB3, PECAM1, PDGFRB, AKT1, FBLN2, ITGA5, FN1, FGG, FGA, NID1, COL1A2, CAPN1, CI
Protein Size: 788

Molecular Weight: 84 kDa

Gene ID: 3690

NCBI Accession: NM_000212, NP_000203

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex