MAD1L1 antibody (N-Term)

Catalog No. ABIN2789565

This Rabbit Polyclonal antibody specifically detects MAD1L1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig and Horse.

Quick Overview for MAD1L1 antibody (N-Term) (ABIN2789565)

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD1L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAD1L1 Antibody

Binding Specificity: N-Term

Purpose: MAD1L1 Antibody - N-terminal region

Sequence: EKQELQEQLD LQHKKCQEAN QKIQELQASQ EARADHEQQI KDLEQKLSLQ

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MAD1L1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MAD1L1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63613-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAD1L1

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Alternative Name: MAD1L1

Background:

Background Information: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.

Alternative Symbols: MAD1, PIG9, TP53I9, TXBP181

Protein Name: Mitotic spindle assembly checkpoint protein MAD1

Molecular Weight: 78kDa

Gene ID: 8379

NCBI Accession: NP_003541

UniProt: Q9Y6D9

Pathways: M Phase