MAD1L1 antibody (N-Term)

Catalog No. ABIN2789565

Product Details anti-MAD1L1 Antibody

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD1L1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKQELQEQLD LQHKKCQEAN QKIQELQASQ EARADHEQQI KDLEQKLSLQ

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MAD1L1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MAD1L1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAD1L1

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Alternative Name: MAD1L1 (MAD1L1 Products)

Synonyms: MAD1 antibody, PIG9 antibody, TP53I9 antibody, TXBP181 antibody, AI173502 antibody, AW550425 antibody, Mad1 antibody, zgc:56571 antibody, MAD1-like protein 1 antibody, mitotic arrest deficient 1 like 1 antibody, MAD1 mitotic arrest deficient like 1 antibody, MAD1 mitotic arrest deficient 1-like 1 antibody, deafness, autosomal recessive 19 antibody, MAD1L1 antibody, Mad1l1 antibody, mad1l1 antibody, DFNB19 antibody

Background: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MAD1, PIG9, TP53I9, TXBP181
Protein Interaction Partner: CWF19L2, HAUS1, TSHZ3, CCDC94, ZSCAN32, CCHCR1, LGALSL, TRIM29, NEBL, USP15, SPATA2, BAG5, RNF8, TPM3, TPM1, PSMA1, MFAP1, TSC22D3, ALOX5, MAD2L1, TRIP13, UBC, TPR, CDC20, ZZEF1, FLNB, SIN3A, METTL21C, ZW10, MAD2L1BP, COIL, CDC27, NRD1, Cdk1, MNT, AMOTL2,
Protein Size: 718

Molecular Weight: 78 kDa

Gene ID: 8379

NCBI Accession: NM_003550, NP_003541

UniProt: Q9Y6D9

Pathways: M Phase