PPCS antibody (C-Term)

Catalog No. ABIN2789588

This Rabbit Polyclonal antibody specifically detects PPCS in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Pig, Dog, Rabbit and Saccharomyces cerevisiae.

Quick Overview for PPCS antibody (C-Term) (ABIN2789588)

Target: PPCS (Phosphopantothenoylcysteine Synthetase (PPCS))

Reactivity: Human, Mouse, Rat, Horse, Pig, Dog, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPCS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPCS Antibody

Binding Specificity: C-Term

Purpose: PPCS Antibody - C-terminal region

Sequence: ANILESRQSF VFIVTKDSET KLLLSEEEIE KGVEIEEKIV DNLQSRHTAF

Predicted Reactivity: Dog: 79%, Horse: 86%, Human: 100%, Mouse: 82%, Pig: 86%, Rabbit: 79%, Rat: 85%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against PPCS. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63677-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPCS

Target: PPCS (Phosphopantothenoylcysteine Synthetase (PPCS))

Alternative Name: PPCS

Background:

Background Information: Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCS (EC 6.3.2.5), one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine.

Gene Name: Phosphopantothenoylcysteine synthetase

Alternative Symbols: CMD2C

Molecular Weight: 31kDa

Gene ID: 79717

NCBI Accession: NP_078940

UniProt: Q9HAB8

Pathways: Ribonucleoside Biosynthetic Process