IL28B antibody (C-Term)

Catalog No. ABIN2789594

Product Details anti-IL28B Antibody

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL28B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRTRGRLHHW LHRLQEAPKK ESPGCLEASV TFNLFRLLTR DLNCVASGDL

Specificity: This antibody is pan-IL28 specific, as there is 100 % homology to the human IL28A sequence, per http://www.uniprot.org/uniprot/Q8IZJ0.

Predicted Reactivity: Dog: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 85%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against IL28B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 196 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL28B

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Alternative Name: IL28B (IL28B Products)

Background: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Alias Symbols: IFNL3, IL-28B, IL28C, IL28B
Protein Interaction Partner: IL10RB,
Protein Size: 196

Molecular Weight: 22 kDa

Gene ID: 282617

NCBI Accession: NM_172139, NP_742151

UniProt: Q8IZI9