RPS3 antibody (C-Term)

Catalog No. ABIN2789596

Product Details anti-RPS3 Antibody

Target: RPS3 (Ribosomal Protein S3 (RPS3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PWDPTGKIGP KKPLPDHVSI VEPKDEILPT TPISEQKGGK PEPPAMPQPV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RPS3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 243 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPS3

Target: RPS3 (Ribosomal Protein S3 (RPS3))

Alternative Name: RPS3 (RPS3 Products)

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus.
Alias Symbols: FLJ26283, FLJ27450, MGC87870, S3
Protein Interaction Partner: HUWE1, UBC, RPS20, RPS12, RPS7, TUBGCP4, CEP250, TUBGCP2, TUBGCP3, CEP57, VCP, TUBG1, AURKA, SUMO2, PPP2R1A, NEDD1, CDC20, RELA, NFKB1, TRAF2, STAU1, CSNK2A1, MDM2, RPS17, EED, EIF3CL, TSR1, SERBP1, LARP1, GNB2L1, EIF3A, DYNLL1, DYNLT3, RPS29, RPS28, RPS2
Protein Size: 243

Molecular Weight: 27 kDa

Gene ID: 6188

NCBI Accession: NM_001005, NP_000996

UniProt: P23396

Pathways: Positive Regulation of Endopeptidase Activity