GADD34 antibody (N-Term)

Catalog No. ABIN2789598

Product Details anti-GADD34 Antibody

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD34 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GMYGEREATS VPRGQGSQFA DGQRAPLSPS LLIRTLQGSD KNPGEEKAEE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP1R15A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 674 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GADD34

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Alternative Name: PPP1R15A (PPP1R15A Products)

Synonyms: 9630030H21 antibody, Gadd34 antibody, Myd116 antibody, GADD34 antibody, Peg-3 antibody, RGD1624209 antibody, protein phosphatase 1 regulatory subunit 15A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 15A antibody, protein phosphatase 1, regulatory subunit 15A antibody, PPP1R15A antibody, Ppp1r15a antibody

Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
Alias Symbols: GADD34
Protein Interaction Partner: Dlg4, ZNF512B, PPP1CA, CTBP2, SMAD7, CAND1, COPS5, CUL3, RAD21, CUEDC2, IKBKB, HABP4, PPP1CC, PPP1R1A, TSN, KIF3A, EIF2S1, BCAR1, POU3F3, SMARCB1, BAG1, LYN, KMT2A, HSPA1A, GLC7, PPP1CB, HSPA8,
Protein Size: 674

Molecular Weight: 74 kDa

Gene ID: 23645

NCBI Accession: NM_014330, NP_055145

UniProt: O75807

Pathways: ER-Nucleus Signaling, Unfolded Protein Response