GADD34 antibody (AA 375-674)

Catalog No. ABIN7269676

This Rabbit Polyclonal antibody specifically detects GADD34 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for GADD34 antibody (AA 375-674) (ABIN7269676)

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD34 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GADD34 Antibody

Binding Specificity: AA 375-674

Purpose: PPP1R15A Rabbit pAb

Sequence: ASSSTPATGV FLKSWVYQPG EDTEEEEDED SDTGSAEDER EAETSASTPP ASAFLKAWVY RPGEDTEEEE DEDVDSEDKE DDSEAALGEA ESDPHPSHPD QRAHFRGWGY RPGKETEEEE AAEDWGEAEP CPFRVAIYVP GEKPPPPWAP PRLPLRLQRR LKRPETPTHD PDPETPLKAR KVRFSEKVTV HFLAVWAGPA QAARQGPWEQ LARDRSRFAR RITQAQEELS PCLTPAARAR AWARLRNPPL APIPALTQTL PSSSVPSSPV QTTPLSQAVA TPSRSSAAAA AALDLSGRRG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 375-674 of human PPP1R15A (NP_055145.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GADD34

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Alternative Name: PPP1R15A

Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.,PPP1R15A,GADD34,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Translation Control,Regulation of eIF2,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,PPP1R15A

Molecular Weight: 49kDa/50kDa 56kDa/73kDa

Gene ID: 23645

UniProt: O75807

Pathways: ER-Nucleus Signaling, Unfolded Protein Response