GADD34 Products
(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
Categories
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008].
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Featured GADD34 Categories
GADD34 Antibodies
High quality antibodies with extensive validation data.
GADD34 ELISA Kits
Reliable ELISA kits for a wide range of species.
GADD34 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GADD34 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, IF
Validations
- (6)
Cat. No.
ABIN184571
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, FACS, IF, IHC (p)
Validations
- (10)
Cat. No.
ABIN1498364
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7269676
Quantity
100 μL
Datasheet
Datasheet
Recommended GADD34 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958942
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958943
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210738
Quantity
96 tests
Datasheet
Datasheet
Recommended GADD34 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124666
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315962
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3094784
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GADD34 products
: "YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma." in: Cell death & disease, Vol. 9, Issue 11, pp. 1108, (2018) (PubMed).: "The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis." in: The Journal of biological chemistry, Vol. 290, Issue 34, pp. 20687-99, (2015) (PubMed).
: "Phosphorylation at tyrosine 262 promotes GADD34 protein turnover." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33146-55, (2013) (PubMed).
: "Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein." in: The Journal of biological chemistry, Vol. 286, Issue 24, pp. 21687-96, (2011) (PubMed).
: "Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication." in: Journal of the National Cancer Institute, Vol. 98, Issue 1, pp. 38-50, (2006) (PubMed).
: "The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 11, pp. 1573-5, (2003) (PubMed).
Synonyms and alternative names related to GADD34
protein phosphatase 1 regulatory subunit 15A (PPP1R15A), protein phosphatase 1, regulatory (inhibitor) subunit 15A (Ppp1r15a), protein phosphatase 1, regulatory subunit 15A (Ppp1r15a), 9630030H21, Gadd34, GADD34, Myd116, Peg-3, RGD1624209Protein level used designations for GADD34
- protein phosphatase 1, regulatory (inhibitor) subunit 15A
- growth arrest and DNA damage-inducible protein GADD34
- growth arrest and DNA-damage-inducible 34
- myeloid differentiation primary response gene 116
- myeloid differentiation primary response protein MyD116
- protein phosphatase 1 regulatory subunit 15A
- myeloid differentiation primary response protein MyD116 homolog
- progression elevated gene 3 protein
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