ICK antibody (C-Term)

Catalog No. ABIN2789615

Product Details anti-ICK Antibody

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RFESVLDLKP SEPVGTGNSA PTQTSYQRRD TPTLRSAAKQ HYLKHSRYLP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ICK. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 632 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ICK

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Alternative Name: ICK (ICK Products)

Synonyms: ICK antibody, ECO antibody, LCK2 antibody, MRK antibody, 2210420N10Rik antibody, AI848300 antibody, Mrk antibody, intestinal cell kinase antibody, intestinal cell (MAK-like) kinase antibody, ICK antibody, ick antibody, Ick antibody

Background: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
Alias Symbols: ECO, KIAA0936, LCK2, MGC46090, MRK
Protein Interaction Partner: TP53, PSMD1, PSMC6, CPSF1, NUP188, ICK, MAPK1, SMAD1, HSP90AA1, CD247, VCP, APP, RPTOR, CDK20, CDC7, BAG6, MNAT1, SUMO1,
Protein Size: 632

Molecular Weight: 71 kDa

Gene ID: 22858

NCBI Accession: NM_014920, NP_055735

UniProt: Q9UPZ9