ICK antibody (C-Term)

Catalog No. ABIN2789615

This Rabbit Polyclonal antibody specifically detects ICK in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for ICK antibody (C-Term) (ABIN2789615)

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ICK Antibody

Binding Specificity: C-Term

Purpose: ICK Antibody - C-terminal region

Sequence: RFESVLDLKP SEPVGTGNSA PTQTSYQRRD TPTLRSAAKQ HYLKHSRYLP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ICK. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63766-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ICK

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Alternative Name: ICK

Background:

Background Information: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

Gene Name: Intestinal cell (MAK-like) kinase

Alternative Symbols: ECO, ICK, MRK, LCK2, hICK, EJM10

Protein Name: Serine/threonine-protein kinase ICK

Molecular Weight: 71kDa

Gene ID: 22858

NCBI Accession: NP_055735

UniProt: Q9UPZ9