THEMIS antibody (C-Term)

Catalog No. ABIN2789620

This Rabbit Polyclonal antibody specifically detects THEMIS in WB. It exhibits reactivity toward Human.

Quick Overview for THEMIS antibody (C-Term) (ABIN2789620)

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEMIS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-THEMIS Antibody

Binding Specificity: C-Term

Purpose: THEMIS Antibody - C-terminal region

Sequence: RHHVDITKKL HPNQAGLDSK VLIGSQNDLV DEEKERSNRG ATAIAETFKN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against THEMIS. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63775-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for THEMIS

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Alternative Name: THEMIS

Background:

Background Information: THEMIS plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. It is required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. It regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

Gene Name: Thymocyte selection associated

Alternative Symbols: GASP, SPOT, TSEPA, C6orf190, C6orf207

Protein Name: Protein THEMIS

Molecular Weight: 66kDa

Gene ID: 387357

NCBI Accession: NP_001158159

UniProt: Q8N1K5