THEMIS antibody (C-Term)
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- Target See all THEMIS Antibodies
- THEMIS (Thymocyte Selection Associated (THEMIS))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This THEMIS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RHHVDITKKL HPNQAGLDSK VLIGSQNDLV DEEKERSNRG ATAIAETFKN
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against THEMIS. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product THEMIS Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 606 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- THEMIS (Thymocyte Selection Associated (THEMIS))
- Alternative Name
- THEMIS (THEMIS Products)
- Synonyms
- TSEPA antibody, C6orf190 antibody, C6orf207 antibody, GASP antibody, SPOT antibody, bA325O24.3 antibody, bA325O24.4 antibody, A430108D01 antibody, BB160712 antibody, E430004N04Rik antibody, Gasp antibody, Tsepa antibody, thylex antibody, C9H6ORF190 antibody, im:7138580 antibody, tsepa antibody, thymocyte selection associated antibody, THEMIS antibody, Themis antibody, themis antibody
- Background
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THEMIS plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. It is required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. It regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Alias Symbols: C6orf190, C6orf207, FLJ40584, MGC163388, TSEPA, bA325O24.3, bA325O24.4, GASP, SPOT
Protein Interaction Partner: UBC, PRMT6,
Protein Size: 606 - Molecular Weight
- 66 kDa
- Gene ID
- 387357
- NCBI Accession
- NM_001164687, NP_001158159
- UniProt
- Q8N1K5
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