TUBB3 antibody (C-Term)

Catalog No. ABIN2789623

This Rabbit Polyclonal antibody specifically detects TUBB3 in WB and IP. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio), Rabbit and Horse.It has been mentioned in 1 publication

Quick Overview for TUBB3 antibody (C-Term) (ABIN2789623)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio), Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-TUBB3 Antibody

Binding Specificity: C-Term

Purpose: TUBB3 Antibody - C-terminal region

Sequence: LHWYTGEGMD EMEFTEAESN MNDLVSEYQQ YQDATAEEEG EMYEDDEEES

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TUBB3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63784-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-TUBB3 antibody (ABIN2789623)

Xavier, Ludwig, Nagai, de Almeida, Watanabe, Hirata, Rosenstock, Papes, Malnic, Glezer: "CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium." in: Scientific reports, Vol. 6, pp. 25507, (2016) (PubMed).

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUBB3

Background:

Background Information: This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.

Gene Name: Tubulin, beta 3 class III

Alternative Symbols: CDCBM, FEOM3, TUBB4, CDCBM1, CFEOM3, beta-4, CFEOM3A

Protein Name: Tubulin beta-3 chain

Molecular Weight: 50kDa

Gene ID: 10381

NCBI Accession: NP_006077

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase