PEX14 antibody (C-Term)

Catalog No. ABIN2789633

The Rabbit Polyclonal anti-PEX14 antibody is suitable to detect PEX14 in samples from Human, Mouse, Rat, Horse, Guinea Pig, Zebrafish (Danio rerio) and Dog. It has been validated for WB.

Quick Overview for PEX14 antibody (C-Term) (ABIN2789633)

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Reactivity: Human, Mouse, Rat, Horse, Guinea Pig, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PEX14 Antibody

Binding Specificity: C-Term

Purpose: PEX14 Antibody - C-terminal region

Sequence: EKREDKEDEE DEEDDDVSHV DEEDCLGVQR EDRRGGDGQI NEQVEKLRRP

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against PEX14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PEX14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63809-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEX14

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Alternative Name: PEX14

Background:

Background Information: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

Gene Name: peroxisomal biogenesis factor 14

Alternative Symbols: NAPP2, PBD13A, Pex14p, dJ734G22.2

Protein Name: Peroxisomal membrane protein PEX14

Molecular Weight: 36kDa

Gene ID: 5195

UniProt: O75381

Pathways: Maintenance of Protein Location