FUT3 antibody (C-Term)

Catalog No. ABIN2789675

The Rabbit Polyclonal anti-FUT3 antibody is suitable to detect FUT3 in samples from Human and Pig. It has been validated for WB.

Quick Overview for FUT3 antibody (C-Term) (ABIN2789675)

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FUT3 Antibody

Binding Specificity: C-Term

Purpose: FUT3 Antibody - C-terminal region

Sequence: RSNYERFLPP DAFIHVDDFQ SPKDLARYLQ ELDKDHARYL SYFRWRETLR

Predicted Reactivity: Human: 100%, Pig: 77%

Characteristics: This is a rabbit polyclonal antibody against FUT3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63942-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FUT3

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Alternative Name: FUT3

Background:

Background Information: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene Name: Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)

Alternative Symbols: LE, Les, FT3B, CD174, FucT-III

Protein Name: Galactoside 3(4)-L-fucosyltransferase

Molecular Weight: 42kDa

Gene ID: 2525

NCBI Accession: NP_000140

UniProt: P21217