PRKCSH antibody (N-Term)

Catalog No. ABIN2789691

The Rabbit Polyclonal anti-PRKCSH antibody (ABIN2789691) specifically detects PRKCSH in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow and Pig samples.

Quick Overview for PRKCSH antibody (N-Term) (ABIN2789691)

Target: PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKCSH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRKCSH Antibody

Binding Specificity: N-Term

Purpose: PRKCSH Antibody - N-terminal region

Sequence: SNRVNDGVCD CCDGTDEYNS GVICENTCKE KGRKERESLQ QMAEVTREGF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PRKCSH. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64007-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRKCSH

Target: PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))

Alternative Name: PRKCSH

Background:

Targeted Subunit: beta

Background Information: This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene Name: Protein kinase C substrate 80K-H

Alternative Symbols: GIIB, PCLD, PLD1, G19P1, PCLD1, PKCSH, AGE-R2, VASAP-60

Protein Name: Glucosidase 2 subunit beta

Molecular Weight: 59kDa

Gene ID: 5589

NCBI Accession: NP_002734

UniProt: P14314

Pathways: Cellular Glucan Metabolic Process, Methionine Biosynthetic Process