ICOSLG antibody (C-Term)

Catalog No. ABIN2789695

The Rabbit Polyclonal anti-ICOSLG antibody is suitable to detect ICOSLG in samples from Human. It has been validated for WB.

Quick Overview for ICOSLG antibody (C-Term) (ABIN2789695)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ICOSLG Antibody

Binding Specificity: C-Term

Purpose: ICOSLG Antibody - C-terminal region

Sequence: YDVVSVLRIA RTPSVNIGCC IENVLLQQNL TVGSQTGNDI GERDKITENP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ICOSLG. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64015-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: ICOSLG

Background:

Background Information: ICOSLG is a ligand for the T-cell-specific cell surface receptor ICOS. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. ICOSLG could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

Gene Name: Inducible T-cell co-stimulator ligand

Alternative Symbols: B7h, B7H2, GL50, B7-H2, B7RP1, CD275, ICOSL, LICOS, B7RP-1, ICOS-L

Protein Name: ICOS ligand

Molecular Weight: 33kDa

Gene ID: 23308

NCBI Accession: NP_056074

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation