MMAA antibody (N-Term)

Catalog No. ABIN2789699

This Rabbit Polyclonal antibody specifically detects MMAA in WB. It exhibits reactivity toward Human, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for MMAA antibody (N-Term) (ABIN2789699)

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMAA Antibody

Binding Specificity: N-Term

Sequence: GQRACLAEAI TLVESTHSRK KELAQVLLQK VLLYHREQEQ SNKGKPLAFR

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MMAA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMAA

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Alternative Name: MMAA

Background: The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria.
Alias Symbols: MGC120010, MGC120011, MGC120012, MGC120013, cblA
Protein Interaction Partner: MMAA, MUT,
Protein Size: 418

Molecular Weight: 46 kDa

Gene ID: 166785

NCBI Accession: NM_172250, NP_758454

UniProt: Q8IVH4

Pathways: Monocarboxylic Acid Catabolic Process