GNB5 antibody (N-Term)

Catalog No. ABIN2789729

Product Details anti-GNB5 Antibody

Target: GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TEGLHENETL ASLKSEAESL KGKLEEERAK LHDVELHQVA ERVEALGQFV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GNB5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 353 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GNB5

Target: GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))

Alternative Name: GNB5 (GNB5 Products)

Synonyms: GB5 antibody, GBS antibody, Gbeta5 antibody, flr antibody, G protein subunit beta 5 antibody, guanine nucleotide binding protein (G protein), beta 5 antibody, GNB5 antibody, Gnb5 antibody

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist.
Alias Symbols: FLJ37457, FLJ43714, GB5
Protein Interaction Partner: MTOR, GNG3, GNG2, GNG13, RGS11, RPA1, PSMD4, E2F2, APP, RGS7BP, CCT5, RGS9, RGS7, PDCL, RGS6, ELAVL1, TSC22D1, CSNK2B, CDKN1A, BNIP3L, ANXA7, GNG4, GNG5, GNG7, OLFM2, PSD, EIF3J, MVD, NR6A1, GNGT1, MCM2, git11,
Protein Size: 353

Molecular Weight: 39 kDa

Gene ID: 10681

NCBI Accession: NM_006578, NP_006569

UniProt: B2RBR5

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling