CCKAR antibody (N-Term)

Catalog No. ABIN2789734

The Rabbit Polyclonal anti-CCKAR antibody is suitable to detect CCKAR in samples from Human, Rat, Mouse, Rabbit, Horse, Cow, Dog and Guinea Pig. It has been validated for WB.

Quick Overview for CCKAR antibody (N-Term) (ABIN2789734)

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Reactivity: Human, Rat, Mouse, Rabbit, Horse, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKAR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCKAR Antibody

Binding Specificity: N-Term

Purpose: CCKAR Antibody - N-terminal region

Sequence: GLENETLFCL DQPRPSKEWQ PAVQILLYSL IFLLSVLGNT LVITVLIRNK

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against CCKAR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64107-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Alternative Name: CCKAR

Background:

Background Information: This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.

Gene Name: Cholecystokinin A receptor

Alternative Symbols: CCK-A, CCK1R, CCKRA, CCK1-R

Protein Name: Cholecystokinin receptor type A

Molecular Weight: 48kDa

Gene ID: 886

NCBI Accession: NP_000721

UniProt: P32238

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour