PCLO antibody (C-Term)

Catalog No. ABIN2789740

The Rabbit Polyclonal anti-PCLO antibody is suitable to detect PCLO in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PCLO antibody (C-Term) (ABIN2789740)

Target: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCLO antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCLO Antibody

Binding Specificity: C-Term

Sequence: SHGIFPDPSK DMQVPTIEKS HSSPGSSKSS SEGHLRSHGP SRSQSKTSVT

Predicted Reactivity: Cow: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PCLO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PCLO

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCLO

Target: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Alternative Name: PCLO

Background: The protein encoded by this gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, CEP72, Dlg4, ERC2, GIT1, GIT2,
Protein Size: 356

Molecular Weight: 39 kDa

Gene ID: 27445

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis