MAGED1 antibody (C-Term)

Catalog No. ABIN2789745

This anti-MAGED1 antibody is a Rabbit Polyclonal antibody detecting MAGED1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Goat and Guinea Pig.

Quick Overview for MAGED1 antibody (C-Term) (ABIN2789745)

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGED1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAGED1 Antibody

Binding Specificity: C-Term

Sequence: ACFVLEKKFG IQLKEIDKEE HLYILISTPE SLAGILGTTK DTPKLGLLLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAGED1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 778 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Alternative Name: MAGED1

Background: This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: DLXIN-1, NRAGE
Protein Interaction Partner: DAB1, CA8, SMAP2, RBM23, RBFOX2, RBPMS, TFG, AKAP9, BAG3, MAGED1, EIF4E2, BHLHE40, UBC, SNRPC, PRKAB2, C1orf94, RHOXF2, CCDC33, KRTAP19-5, TTC32, ZNF488, BIRC8, TTC23, MEOX2, MDFI, KPNA2, RBFOX1, FBXO7, CEP250, MAGED2, TAB1, MAP3K7, MAPK3, PITX1, XIAP, IR
Protein Size: 778

Molecular Weight: 86 kDa

Gene ID: 9500

NCBI Accession: NM_006986, NP_008917

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway