NTSR2 antibody (C-Term)
Quick Overview for NTSR2 antibody (C-Term) (ABIN2789746)
Target
See all NTSR2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- NTSR2 Antibody - C-terminal region
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Sequence
- AFLNGVTVSH LLALCSQVPS TSTPGSSTPS RLELLSEEGL LSFIVWKKTF
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Predicted Reactivity
- Horse: 77%, Human: 100%, Yeast: 85%
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Characteristics
- This is a rabbit polyclonal antibody against NTSR2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64147-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- prevent freeze-thaw cycles
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Storage
- 4 °C,-20 °C
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Storage Comment
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NTSR2 (Neurotensin Receptor 2 (NTSR2))
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Alternative Name
- NTSR2
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Background
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Background Information: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
Gene Name: Neurotensin receptor 2
Alternative Symbols: NTR2
Protein Name: Neurotensin receptor type 2
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Molecular Weight
- 45kDa
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Gene ID
- 23620
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NCBI Accession
- NP_036476
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UniProt
- O95665
Target
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