SUMF1 antibody (N-Term)

Catalog No. ABIN2789756

This Rabbit Polyclonal antibody specifically detects SUMF1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for SUMF1 antibody (N-Term) (ABIN2789756)

Target: SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SUMF1 Antibody

Binding Specificity: N-Term

Purpose: SUMF1 Antibody - N-terminal region

Sequence: SREANAPGPV PGERQLAHSK MVPIPAGVFT MGTDDPQIKQ DGEAPARRVT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SUMF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SUMF1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64172-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUMF1

Target: SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))

Alternative Name: SUMF1

Background:

Background Information: This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Gene Name: sulfatase modifying factor 1

Alternative Symbols: FGE, UNQ3037, AAPA3037

Protein Name: Sulfatase-modifying factor 1

Molecular Weight: 41 kDa

Gene ID: 285362

NCBI Accession: NP_877437

UniProt: Q8NBK3