JIP3 antibody (N-Term)

Catalog No. ABIN2789770

The Rabbit Polyclonal anti-JIP3 antibody (ABIN2789770) specifically detects JIP3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio) samples.

Quick Overview for JIP3 antibody (N-Term) (ABIN2789770)

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JIP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JIP3 Antibody

Binding Specificity: N-Term

Purpose: MAPK8IP3 Antibody - N-terminal region

Sequence: QYEREKALRR QAEEKFIEFE DALEQEKKEL QIQVEHYEFQ TRQLELKAKN

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MAPK8IP3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64220-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for JIP3

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Alternative Name: MAPK8IP3

Background:

Background Information: The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport.

Gene Name: Mitogen-activated protein kinase 8 interacting protein 3

Alternative Symbols: syd, JIP3, SYD2, JIP-3, JSAP1, NEDBA

Protein Name: C-Jun-amino-terminal kinase-interacting protein 3 Ensembl ENSP00000348290

Molecular Weight: 147kDa

Gene ID: 23162

NCBI Accession: NP_001035529

UniProt: E9PFH7