CDK2AP1 antibody (C-Term)
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- Target See all CDK2AP1 Antibodies
- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK2AP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LLAIIEELGK EIRPTYAGSK SAMERLKRGI IHARGLVREC LAETERNARS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against CDK2AP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK2AP1
- Top Product
- Discover our top product CDK2AP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 115 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
- Alternative Name
- CDK2AP1 (CDK2AP1 Products)
- Synonyms
- MGC64532 antibody, doc1 antibody, st19 antibody, doc-1 antibody, dorc1 antibody, p12doc-1 antibody, Apc10 antibody, Cdkap1 antibody, DORC1 antibody, Doc1 antibody, ST19 antibody, p12 antibody, DOC1 antibody, p12DOC-1 antibody, cyclin-dependent kinase 2 associated protein 1 S homeolog antibody, cyclin dependent kinase 2 associated protein 1 antibody, cyclin dependent kinase 2 associated protein 1 pseudogene antibody, cyclin-dependent kinase 2 associated protein 1 antibody, CDK2 (cyclin-dependent kinase 2)-associated protein 1 antibody, cdk2ap1.S antibody, CDK2AP1 antibody, LOC475806 antibody, cdk2ap1 antibody, Cdk2ap1 antibody
- Background
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The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Alias Symbols: DOC1, DORC1, ST19, doc-1, p12DOC-1
Protein Interaction Partner: MRFAP1L1, CCDC136, HDAC2, HDAC1, ZNF420, MTA3, VCP, CDK2AP2, Cebpb, HHV8GK18_gp81, ELAVL1, MBD3, MBD2, RBBP7, RBBP4, SRRM2, POLA1, CDK2, IGHA2, IGHA1, AMY1A,
Protein Size: 115 - Molecular Weight
- 12 kDa
- Gene ID
- 8099
- NCBI Accession
- NM_004642, NP_004633
- UniProt
- O14519
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