Nth Endonuclease III-Like 1 (NTHL1) (N-Term) antibody

Catalog No. ABIN2789777

The Rabbit Polyclonal anti-Nth Endonuclease III-Like 1 antibody is suitable to detect Nth Endonuclease III-Like 1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Pig. It has been validated for WB.

Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) (N-Term) antibody (ABIN2789777)

Target: Nth Endonuclease III-Like 1 (NTHL1)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Sequence: DWQQQLVNIR AMRNKKDAPV DHLGTEHCYD SSAPPKVRRY QVLLSLMLSS

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 87%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against NTHL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NTHL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 312 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Nth Endonuclease III-Like 1 (NTHL1)

Alternative Name: NTHL1

Background: The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
Alias Symbols: NTH1, OCTS3
Protein Interaction Partner: FAM96B, RPA3, RPA2, RPA1, HECW2, MMS19, ZC3HAV1, UBC, ERCC5, RNMTL1, GAPDHS, MYH7, MYH4, NUDT1, TP53,
Protein Size: 312

Molecular Weight: 34 kDa

Gene ID: 4913

NCBI Accession: NM_002528, NP_002519

UniProt: P78549