CFC1 antibody (N-Term)

Catalog No. ABIN2789795

This Rabbit Polyclonal antibody specifically detects CFC1 in WB. It exhibits reactivity toward Human, Rat and Horse.

Quick Overview for CFC1 antibody (N-Term) (ABIN2789795)

Target: CFC1 (Cripto, FRL-1, Cryptic Family 1 (CFC1))

Reactivity: Human, Rat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFC1 Antibody

Binding Specificity: N-Term

Purpose: CFC1 Antibody - N-terminal region

Sequence: IINLGNSYQR EKHNGGREEV TKVATQKHRQ SPLNWTSSHF GEVTGSAEGW

Predicted Reactivity: Horse: 86%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CFC1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64298-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFC1

Target: CFC1 (Cripto, FRL-1, Cryptic Family 1 (CFC1))

Alternative Name: CFC1

Background:

Background Information: This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. These proteins play key roles in intercellular signaling pathways during vertebrate embryogenesis. Mutations in this gene can cause autosomal visceral heterotaxy. This protein is involved in left-right asymmetric morphogenesis during organ development.

Gene Name: Cripto, FRL-1, cryptic family 1

Alternative Symbols: HTX2, CFC1B, DTGA2, CRYPTIC

Protein Name: Cryptic protein

Molecular Weight: 25kDa

Gene ID: 55997

NCBI Accession: NP_115934

UniProt: P0CG37