NCF2 antibody (C-Term)

Catalog No. ABIN2789807

The Rabbit Polyclonal anti-NCF2 antibody (ABIN2789807) specifically detects NCF2 in WB. The antibody is reactive with Human, Cow, Dog, Guinea Pig and Rabbit samples.

Quick Overview for NCF2 antibody (C-Term) (ABIN2789807)

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Reactivity: Human, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCF2 Antibody

Binding Specificity: C-Term

Purpose: NCF2 Antibody - C-terminal region

Sequence: TVGDQGFPDE PKESEKADAN NQTTEPQLKK GSQVEALFSY EATQPEDLEF

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rabbit: 75%

Characteristics: This is a rabbit polyclonal antibody against NCF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NCF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64332-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCF2

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Alternative Name: NCF2

Background:

Background Information: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

Alternative Symbols: NCF-2, NOXA2, P67PHOX, P67-PHOX

Protein Name: Neutrophil cytosol factor 2

Molecular Weight: 60kDa

Gene ID: 4688

NCBI Accession: NP_000424

UniProt: P19878