RCN1 antibody (C-Term)

Catalog No. ABIN2789815

This Rabbit Polyclonal antibody specifically detects RCN1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for RCN1 antibody (C-Term) (ABIN2789815)

Target: RCN1 (Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RCN1 Antibody

Binding Specificity: C-Term

Purpose: RCN1 Antibody - C-terminal region

Sequence: QAEARHLVYE SDKNKDEKLT KEEILENWNM FVGSQATNYG EDLTKNHDEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against RCN1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64355-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RCN1

Target: RCN1 (Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1))

Alternative Name: RCN1

Background:

Background Information: Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.

Gene Name: Reticulocalbin 1, EF-hand calcium binding domain

Alternative Symbols: RCN, RCAL, PIG20, HEL-S-84

Protein Name: Reticulocalbin-1

Molecular Weight: 39kDa

Gene ID: 5954

NCBI Accession: NP_002892

UniProt: Q15293