PDE4C antibody (C-Term)

Catalog No. ABIN2789817

Product Details anti-PDE4C Antibody

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RIMAEFFQQG DRERESGLDI SPMCDKHTAS VEKSQVGFID YIAHPLWETW

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PDE4C. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 606 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE4C

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Alternative Name: PDE4C (PDE4C Products)

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: DPDE1, MGC126222
Protein Interaction Partner: SRI, UBC,
Protein Size: 606

Molecular Weight: 68 kDa

Gene ID: 5143

NCBI Accession: NM_001098819, NP_001092289

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process