ATG13 antibody (N-Term)
Quick Overview for ATG13 antibody (N-Term) (ABIN2789823)
Target
See all ATG13 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- MCVEISLKTS EGDSMELEIW CLEMNEKCDK EIKVSYTVYN RLSLLLKSLL
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Characteristics
- This is a rabbit polyclonal antibody against ATG13. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATG13
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 480 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATG13 (Autophagy Related 13 (ATG13))
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Alternative Name
- ATG13
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Background
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ATG13 is an autophagy factor required for autophagosome formation. ATG13 is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
Alias Symbols: ATG13, FLJ20698, KIAA0652
Protein Interaction Partner: SESN2, ATG16L1, MAP1LC3A, ATG101, GABARAP, AMBRA1, ULK1, APP, MAP1LC3C, TAB3, MAP1LC3B, GABARAPL1, TAB2, GABARAPL2, UBC, RB1CC1,
Protein Size: 480 -
Molecular Weight
- 53 kDa
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Gene ID
- 9776
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NCBI Accession
- NM_014741, NP_055556
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UniProt
- O75143
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Pathways
- PI3K-Akt Signaling, Autophagy
Target
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