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ATG13 antibody (N-Term)

This anti-ATG13 antibody is a Rabbit Polyclonal antibody detecting ATG13 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).
Catalog No. ABIN2789823

Quick Overview for ATG13 antibody (N-Term) (ABIN2789823)

Target

See all ATG13 Antibodies
ATG13 (Autophagy Related 13 (ATG13))

Reactivity

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Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This ATG13 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

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    N-Term

    Sequence

    MCVEISLKTS EGDSMELEIW CLEMNEKCDK EIKVSYTVYN RLSLLLKSLL

    Predicted Reactivity

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    Characteristics

    This is a rabbit polyclonal antibody against ATG13. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATG13
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 480 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    ATG13 (Autophagy Related 13 (ATG13))

    Alternative Name

    ATG13

    Background

    ATG13 is an autophagy factor required for autophagosome formation. ATG13 is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
    Alias Symbols: ATG13, FLJ20698, KIAA0652
    Protein Interaction Partner: SESN2, ATG16L1, MAP1LC3A, ATG101, GABARAP, AMBRA1, ULK1, APP, MAP1LC3C, TAB3, MAP1LC3B, GABARAPL1, TAB2, GABARAPL2, UBC, RB1CC1,
    Protein Size: 480

    Molecular Weight

    53 kDa

    Gene ID

    9776

    NCBI Accession

    NM_014741, NP_055556

    UniProt

    O75143

    Pathways

    PI3K-Akt Signaling, Autophagy
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