PDE7A antibody (C-Term)

Catalog No. ABIN2789835

The Rabbit Polyclonal anti-PDE7A antibody has been validated for WB. It is suitable to detect PDE7A in samples from Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for PDE7A antibody (C-Term) (ABIN2789835)

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE7A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE7A Antibody

Binding Specificity: C-Term

Sequence: DRGDLCLEDT RHRHLVLQMA LKCADICNPC RTWELSKQWS EKVTEEFFHQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PDE7A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDE7A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 482 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE7A

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Alternative Name: PDE7A

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: HCP1, PDE7
Protein Size: 482

Molecular Weight: 55 kDa

Gene ID: 5150

NCBI Accession: NM_001242318, NP_001229247

UniProt: Q13946

Pathways: cAMP Metabolic Process