PDE7A antibody (C-Term)

Catalog No. ABIN2789835

The Rabbit Polyclonal anti-PDE7A antibody is suitable to detect PDE7A in samples from Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PDE7A antibody (C-Term) (ABIN2789835)

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE7A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE7A Antibody

Binding Specificity: C-Term

Purpose: PDE7A Antibody - C-terminal region

Sequence: DRGDLCLEDT RHRHLVLQMA LKCADICNPC RTWELSKQWS EKVTEEFFHQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PDE7A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDE7A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64421-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE7A

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Alternative Name: PDE7A

Background:

Background Information: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative Symbols: HCP1, PDE7

Protein Name: High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

Molecular Weight: 55kDa

Gene ID: 5150

NCBI Accession: NP_001229247

UniProt: Q13946

Pathways: cAMP Metabolic Process