AQR antibody (C-Term)

Catalog No. ABIN2789836

This Rabbit Polyclonal antibody specifically detects AQR in WB. It exhibits reactivity toward Human and Horse.

Quick Overview for AQR antibody (C-Term) (ABIN2789836)

Target: AQR (Aquarius Homolog (AQR))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AQR Antibody

Binding Specificity: C-Term

Purpose: AQR Antibody - C-terminal region

Sequence: DTTPSETGAT STPEAIPALS ETTPTVVGAV SAPAEANTPQ DATSAPEETK

Predicted Reactivity: Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against AQR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64428-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AQR

Target: AQR (Aquarius Homolog (AQR))

Alternative Name: AQR

Background:

Background Information: AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.

Gene Name: Aquarius homolog (mouse)

Alternative Symbols: IBP160, fSAP164

Protein Name: Intron-binding protein aquarius

Molecular Weight: 171kDa

Gene ID: 9716

NCBI Accession: NP_055506

UniProt: O60306