AQR antibody (C-Term)

Catalog No. ABIN2789836

Product Details anti-AQR Antibody

Target: AQR (Aquarius Homolog (AQR))

Binding Specificity: C-Term

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DTTPSETGAT STPEAIPALS ETTPTVVGAV SAPAEANTPQ DATSAPEETK

Predicted Reactivity: Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against AQR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1485 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AQR

Target: AQR (Aquarius Homolog (AQR))

Alternative Name: AQR (AQR Products)

Synonyms: AW495846 antibody, mKIAA0560 antibody, IBP160 antibody, fSAP164 antibody, aquarius antibody, aquarius intron-binding spliceosomal factor antibody, Aqr antibody, AQR antibody

Background: AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Alias Symbols: DKFZp686B23123, IBP160, KIAA0560, fSAP164
Protein Interaction Partner: UBC, LGR4, SUZ12, RNF2, BMI1, ZNF830, WDR83, WDR77, RBM22, PQBP1, RBM4, EIF4A3, MAGOH, SIRT7, HNRNPA1, Prpf8, Cdc5l, Snw1, USP28,
Protein Size: 1485

Molecular Weight: 171 kDa

Gene ID: 9716

NCBI Accession: NM_014691, NP_055506

UniProt: O60306