GPR68 antibody (Middle Region)

Catalog No. ABIN2789838

This Rabbit Polyclonal antibody specifically detects GPR68 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Rabbit, Dog and Pig.

Quick Overview for GPR68 antibody (Middle Region) (ABIN2789838)

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR68 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPR68 Antibody

Binding Specificity: Middle Region

Purpose: GPR68 Antibody - middle region

Sequence: SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL

Predicted Reactivity: Dog: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GPR68. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GPR68

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64436-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Alternative Name: GPR68

Background:

Background Information: Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.

Gene Name: G protein-coupled receptor 68

Alternative Symbols: OGR1, AI2A6, GPR12A

Protein Name: Ovarian cancer G-protein coupled receptor 1

Molecular Weight: 41kDa

Gene ID: 8111

NCBI Accession: NP_003476

UniProt: Q15743