GPR68 antibody (Middle Region)

Catalog No. ABIN2789838

Product Details anti-GPR68 Antibody

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR68 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL

Predicted Reactivity: Dog: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GPR68. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GPR68

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Alternative Name: GPR68 (GPR68 Products)

Synonyms: GPR68 antibody, GPR12A antibody, OGR1 antibody, BB131428 antibody, Ogr1 antibody, G protein-coupled receptor 68 antibody, GPR68 antibody, LOC100348269 antibody, Gpr68 antibody

Background: Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Alias Symbols: MGC111379, MGC156983, OGR1, GPR12A
Protein Size: 365

Molecular Weight: 41 kDa

Gene ID: 8111

NCBI Accession: NM_003485, NP_003476

UniProt: Q15743