JAM2 antibody (Middle Region)

Catalog No. ABIN2789839

The Rabbit Polyclonal anti-JAM2 antibody has been validated for WB. It is suitable to detect JAM2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for JAM2 antibody (Middle Region) (ABIN2789839)

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JAM2 Antibody

Binding Specificity: Middle Region

Sequence: LVAPAVPSCE VPSSALSGTV VELRCQDKEG NPAPEYTWFK DGIRLLENPR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against JAM2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human JAM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 298 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for JAM2

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Alternative Name: JAM2

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
Alias Symbols: C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM
Protein Interaction Partner: JAM3, JAM2, CSNK1A1L, TDP2, SOX8, YBX1, NME3, GPR20, F2RL2, TJP1, PARD3,
Protein Size: 298

Molecular Weight: 31 kDa

Gene ID: 58494

NCBI Accession: NM_021219, NP_067042

UniProt: P57087