JAM2 antibody

Catalog No. ABIN2855842

This Rabbit Polyclonal antibody specifically detects JAM2 in WB, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for JAM2 antibody (ABIN2855842)

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-JAM2 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to JAM-B (junctional adhesion molecule 2)
JAM-B antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human JAM-B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for JAM2

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Alternative Name: junctional adhesion molecule 2

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Cellular Localization: Cell junction , tight junction (By similarity) , Cell membrane, Single-pass type I membrane protein (By similarity)

Molecular Weight: 33 kDa

Gene ID: 58494

UniProt: P57087